C. Adler

Intratumoral mregDC and CXCL13 T helper niches enable local differentiation of CD8 T cells following PD-1 blockade

The paper identifies intratumoral niches involving mregDC and CXCL13+ Th cells that support CD8 T cell differentiation following PD-1 blockade in HCC patients.

Two independent loss-of-function mutations in anthocyanidin synthase homeologous genes make sweet basil all green

The paper identifies two loss-of-function mutations in homeologous anthocyanidin synthase genes that cause sweet basil to be green by preventing anthocyanin production.

Convergent evolution of genome guardian functions in a parasite-specific p53 homolog

This study investigates two P53 homologs in Schistosoma mansoni, finding one orthologous to canonical P53 and another parasite-specific paralog involved in genotoxic stress response, suggesting convergent evolution.

Molecular taxonomy of human ocular outflow tissues defined by single cell transcriptomics

This study uses single-cell RNA sequencing to create a cell atlas of human ocular outflow tissues, identifying 12 cell types and mapping glaucoma-related gene expression.

Laboratory contamination over time during low-biomass sample analysis

This study examines laboratory contamination in low-biomass samples over time, finding that contaminants vary by lab, season, and extraction method, and recommends controls and reporting to mitigate their impact.

Ancient symbiosis confers desiccation resistance to stored grain pest beetles

The paper shows ancient bacterial symbionts in beetles enhance desiccation resistance by altering cuticle properties, aiding survival in dry environments.