Author

J.-B. Lee

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

A. Ayyaz· 1 shared A. Malik· 1 shared B. M. Britton· 1 shared D. Dervovic· 1 shared D. Schramek· 1 shared E. L. Y. Chen· 1 shared G. Mbamalu· 1 shared H. W. Jackson· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperCancer Biology

A. Ayyaz

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Author profile →

3 papers

Recent·Most cited

Enhancing Bone Regeneration and Osseointegration using rhPTH(1-34) and Dimeric R25CPTH(1-34) in an Osteoporotic Beagle Model

J.-O. Shin, J.-b. Lee, S. Lee, J. Kim

This study compares the effects of rhPTH(1-34) and dimeric R25CPTH(1-34) on bone regeneration and osseointegration in an osteoporotic beagle model, finding both improve bone parameters with the dimeric analog showing less pronounced but significant benefits.

bioRxiv · Feb 10, 2024Pathology

In vivo CRISPR screens reveal Serpinb9 and Adam2 as regulators of immune therapy response in lung cancer

D. Dervovic, E. L. Y. Chen, A. Malik, S. Afiuni, J. Boucher, J. M. Berman, K. Teng, A. Ayyaz, Y. Lu, M. Narimatsu, G. Mbamalu, S. Loganathan, S. Martinez, R. Tsai, J.-B. Lee, , D. Schramek

The paper uses in vivo CRISPR screens to identify Serpinb9 and Adam2 as genes regulating immune therapy response in lung cancer, showing their roles in immune suppression and enhancement.

bioRxiv · Mar 13, 2022Cancer Biology

The Formation of a Stable Sliding Clamp Discriminates MSH2-MSH3 and MSH2-MSH6 Mismatch Interaction

B. M. Britton, J. A. London, J. Martin-Lopez, N. D. Jones, J. Liu, J.-B. Lee, R. Fishel

The paper distinguishes MSH2-MSH3 and MSH2-MSH6 mismatch interactions using a high-throughput FRET system based on ATP-bound sliding clamp stability.

bioRxiv · Oct 21, 2021 · PreprintBiochemistry