Author

R. Goetzke

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Research Focus:differential expression· 2 Assay:DNA methylation· 2 Assay:scRNA-seq· 2 Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1

Frequent Co-Authors

W. Wagner· 4 shared M. Zenke· 3 shared K. Zeevaert· 2 shared M. H. Elsafi Mabrouk· 2 shared A. Gillner· 1 shared A. Maurer· 1 shared A. Reiter· 1 shared A. S. Sechi· 1 shared

Activity by Year

2018-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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4 shared papersCell Biology

W. Wagner

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

YAP1 is essential for self-organized differentiation of pluripotent stem cells

K. Zeevaert, R. Goetzke, M. H. Elsafi Mabrouk, M. Schmidt, C. Maassen, A.-C. Henneke, C. He, A. Gillner, M. Zenke, W. Wagner

This study shows YAP1 is critical for germ layer specification in iPSCs, particularly in self-organized embryoid bodies, through NODAL pathway activation.

bioRxiv · Sep 29, 2022Cell Biology

The spatial self-organization within pluripotent stem cell colonies is continued in detaching aggregates

M. H. Elsafi Mabrouk, R. Goetzke, G. Abagnale, B. Yesilyurt, L. Salz, K. Zeevaert, Z. Ma, M. A. S. Toledo, R. Li, I. G. Costa, V. Pachauri, U. Schnakenberg, M. Zenke, W. Wagner

The paper shows that self-organization in iPSC colonies continues in 3D aggregates formed after detachment from substrates, with maintained gene expression patterns.

Biomaterials · Mar 1, 2022Peer-reviewedCell Biology

Nintedanib Targets KIT D816V Neoplastic Cells Derived from Induced Pluripotent Stem cells of Systemic Mastocytosis

M. A. Szymanski de Toledo, M. Gatz, S. Sontag, K. V. Gleixer, G. Eisenwort, K. Feldberg, F. Kluge, R. Guareschi, G. Rossetti, A. S. Sechi, O. Dufva, S. M. Mustjoki, A. Maurer, H. M. Schueler, R. Goetzke, , M. Zenke

This study identifies nintedanib as a novel KIT D816V inhibitor effective against patient-derived neoplastic mast cells in systemic mastocytosis.

bioRxiv · May 6, 2020Cancer Biology

Interrupted reprogramming into induced pluripotent stem cells does not rejuvenate human mesenchymal stromal cells

C. Goebel, R. Goetzke, T. Eggermann, W. Wagner

This study shows that interrupting reprogramming of mesenchymal stromal cells into iPSCs does not rejuvenate the cells and may lead to chromosomal abnormalities.

bioRxiv · Jun 12, 2018Cell Biology