The spatial self-organization within pluripotent stem cell colonies is continued in detaching aggregates
M. H. Elsafi Mabrouk, R. Goetzke, G. Abagnale, B. Yesilyurt, L. Salz, K. Zeevaert, Z. Ma, M. A. S. Toledo, R. Li, I. G. Costa, V. Pachauri, U. Schnakenberg, M. Zenke, W. Wagner
The paper shows that self-organization in iPSC colonies continues in 3D aggregates formed after detachment from substrates, with maintained gene expression patterns.
Biomaterials · Mar 1, 2022Peer-reviewedCell Biology