PathologybioRxivPreprint
The PMK-3 (p38) Mitochondrial Retrograde Response Functions in Intestinal Cells to Extend Life via the ESCRT Machinery.
O. Radetskaya, R. K. Lane, T. Friedman…·S. L. Rea
This study identifies PMK-3 as a key regulator of life extension in C. elegans following mitochondrial ETC disruption, showing its reliance on ESCRT machinery for cellular signaling.
DOI 10.1101/797308