Cancer BiologybioRxivPreprint
Notch1 regulates breast cancer stem cell function via a non-canonical cleavage-independent pathway
L. Sui, S. Wang, R. K. Rodriguez…·R. S. Watnick
This study identifies a non-canonical Notch1 pathway that represses SIRT1 to drive tumor initiation and chemoresistance in breast cancer stem cells.
DOI 10.1101/2020.02.28.970764