MicrobiologybioRxivPreprint
Structural basis for kinase inhibition in the tripartite E. coli HipBST toxin-antitoxin system
R. L. Baerentsen, S. V. Nielsen, R. B. Skjerning…·D. E. Brodersen
The paper investigates the structural basis of kinase inhibition in the E. coli HipBST toxin-antitoxin system, showing how HipS inhibits HipT through active site insertion and how phosphorylation affects complex flexibility.
DOI 10.1101/2022.01.28.478185