Author

R. L. Beijersbergen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell type annotation· 2 Research Focus:drug response / drug discovery· 2 Assay:bulk RNA-seq· 1 Assay:DNA methylation· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

C. Lieftink· 4 shared A. Velds· 2 shared B. Morris· 2 shared E. Gogola· 2 shared F. Jochems· 2 shared G. De Conti· 2 shared J. Bhin· 2 shared J. Jonkers· 2 shared

Activity by Year

2021-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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4 shared papersCancer Biology

C. Lieftink

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Cancer BiologybioRxivSep 7, 2022

Multi-omics analysis reveals distinct non-reversion mechanisms of PARPi resistance in BRCA1- versus BRCA2-deficient mammary tumors

J. Bhin, M. Paes Dias, E. Gogola…·J. Jonkers

DOI 10.1016/j.celrep.2023.112538

mousebulk RNA-seq

𝕏 PostBluesky

Cancer BiologybioRxivDec 20, 2021

Genetic and compound screens uncover factors modulating cancer cell response to indisulam

Z. Pogacar, K. Groot, F. Jochems…·R. Leite de Oliveira

This study identifies genetic and compound factors that modulate cancer cell response to the drug indisulam, revealing therapeutic strategies for its clinical reuse.

DOI 10.26508/lsa.202101348

humangenetic perturbation / CRISPR

𝕏 PostBluesky

Cancer BiologybioRxivOct 18, 2021

Indisulam synergizes with palbociclib to induce senescence through inhibition of CDK2 kinase activity

Z. Pogacar, J. L. Johnson, L. Krenning…·R. Leite de Oliveira

The paper identifies that combining indisulam with palbociclib enhances senescence in cancer cells by inhibiting CDK2 kinase activity.

DOI 10.1371/journal.pone.0273182

humanexperimental assay

𝕏 PostBluesky

Cancer BiologybioRxivPreprintMar 24, 2021

Loss of Nuclear DNA Ligase III Reverts PARP Inhibitor Resistance in BRCA1/53BP1 Double-deficient Cells by Exposing ssDNA Gaps

M. Paes Dias, V. Tripathi, I. v. d. Heijden…·J. Jonkers

This study identifies loss of LIG3 as a factor that reverts PARP inhibitor resistance in BRCA1/53BP1 double-deficient cells by increasing ssDNA gaps.

DOI 10.1101/2021.03.24.436323

humanDNA methylation

𝕏 PostBluesky