Cell BiologybioRxiv
In silico APC/C substrate discovery reveals cell cycle degradation of chromatin regulators including UHRF1
J. Kernan, R. C. Martinez-Chacin, X. Wang…·M. J. Emanuele
The paper predicts APC/C substrates in silico, identifies chromatin regulators as substrates, and shows their cell cycle-dependent degradation and impact on DNA methylation.
DOI 10.1371/journal.pbio.3000975