A Wnt5a-Cdc42 axis controls aging and rejuvenation of hair-follicle stem cells
R. L. Tiwari, P. Mishra, N. Martin…·H. Geiger
This study identifies a Wnt5a-Cdc42 signaling axis that regulates hair-follicle stem cell aging and rejuvenation, showing that inhibiting Cdc42 activity restores canonical Wnt signaling and promotes hair regeneration.