MicrobiologybioRxiv
Staphylococcal protein A inhibits complement activation by interfering with IgG hexamer formation
A. R. Cruz, M. A. den Boer, J. Strasser…·S. H. M. Rooijakkers
This study shows Staphylococcal protein A inhibits IgG hexamer formation, blocking complement activation, but IgG3 can still induce complement activation despite SpA.
DOI 10.1073/pnas.2016772118