Cancer BiologybioRxiv
Indirect CRISPR screening with photoconversion revealed key factors of drug resistance with cell-cell interactions
K. Sugita, I. Onishi, R. Nakayama…·M. Kurata
This study uses indirect CRISPR screening with photoconversion to identify key factors of drug resistance mediated by cell-cell interactions, finding genes that reduce cancer cell apoptosis when knocked out in supporting cells.
DOI 10.1038/s42003-023-04941-9