Cystathionine-β-synthase is essential for AKT-induced senescence and suppresses the development of gastric cancers with PI3K/AKT activation
J. Kang, R. Pearson, H. Zhu, K. T. Chan, X. Huang, S. Blake, A. S. Trigos, D. Anderson, D. J. S. Creek, D. P. De Souza, X. Wang, C. Fu, M. Jana, E. Sanij
This study shows that Cystathionine-β-synthase (CBS) maintains AKT-induced senescence and suppresses gastric cancer growth in PI3K/AKT-activated cells.
bioRxiv · Jul 4, 2021Cell Biology