Author

R. R. Du

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

M. Bathe· 2 shared A. A. Burds· 1 shared B. Neun· 1 shared C. Sanders· 1 shared E. Cedrone· 1 shared E. Edmondson· 1 shared E.-C. Wamhoff· 1 shared G. A. Knappe· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersPharmacology & Toxicology

M. Bathe

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2 papers

Recent·Most cited

Pharmacology & ToxicologybioRxivPreprintFeb 25, 2023

Evaluation of non-modified wireframe DNA origami for acute toxicity and biodistribution in mice

E.-C. Wamhoff, G. A. Knappe, A. A. Burds…·M. Bathe

This study evaluates the acute toxicity and biodistribution of non-modified wireframe DNA origami nanoparticles in mice, finding no toxicity and minimal immunotoxicity.

DOI 10.1101/2023.02.25.530026

mouseexperimental assay

𝕏 PostBluesky

BioengineeringbioRxivJul 8, 2022

Innate Immune Stimulation using 3D Wireframe DNA Origami

R. R. Du, E. Cedrone, M. A. Dobrovolskaia, M. Bathe

This study investigates how 3D wireframe DNA origami stimulate the TLR9 pathway, finding that multivalent CpG display enhances immune activation while bare structures do not.

DOI 10.1021/acsnano.2c06275

DNA methylationexperimental assay

𝕏 PostBluesky