Cell BiologybioRxiv
Extracellular Matrix Dysfunction in Sorsby Patient-Derived Retinal Pigment Epithelium
A. L. Engel, Y. Wang, T. Khuu…·J. R. Chao
This study examines SFD patient-derived iPSC-RPE for extracellular matrix dysfunction and oxidative stress, finding increased sub-RPE deposits and elevated 4-hydroxyproline levels.
DOI 10.1016/j.exer.2021.108899