Author

R. Ravindran

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 2 Immunology· 1 Scientific Communication & Education· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Assay:bulk RNA-seq· 3 Organism:mouse· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell signaling & trafficking· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

A. K. G. Velikkakath· 2 shared P. Lowenstein· 2 shared S. M. Srinivasula· 2 shared A. Chandrasekharan· 1 shared A. Chinnaiyan· 1 shared A. Easton· 1 shared A. Geremia· 1 shared B. Mullan· 1 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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2 shared papersCell Biology

A. K. G. Velikkakath

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6 papers

Recent·Most cited

Peroxisome biogenesis initiated by protein phase separation

R. Ravindran, I. O. L. Bacellar, X. Castellanos-Girouard, Z. Zhang, L. Kisley, S. W. Michnick

This study shows that Pex13 and Pex5 undergo liquid-liquid phase separation to form transient transport channels for cargo into peroxisomes.

bioRxiv · Sep 20, 2022Cell Biology

Therapeutic reversal of prenatal pontine ID1 signaling in DIPG

V. N. Yadav, M. K. Harris, D. Messinger, C. Thomas, J. R. Cummings, T. Yang, R. Woo, R. Siddaway, M. Burkert, S. Stallard, T. Qin, B. Mullan, R. Siada, R. Ravindran, M. Niculcea, , C. Koschmann

This study identifies ID1 upregulation in DIPG tumor cells and shows that CBD can reduce ID1-driven invasiveness in vitro and in vivo.

bioRxiv · May 10, 2021 · PreprintCancer Biology

IL-1-driven stromal-neutrophil interaction in deep ulcers defines a pathotype of therapy non-responsive inflammatory bowel disease

M. Friedrich, M. Pohin, M. A. Jackson, I. Korsunsky, S. Bullers, K. Rue-Albrecht, Z. Christoforidou, D. Santhananthan, R. Ravindran, R. Sanches Peres, H. Sharpe, K. Wei, G. F. M. Watts, E. H. Mann, A. Geremia, , F. M. Powrie

bioRxiv · Feb 5, 2021 · PreprintImmunology

Endosomes facilitate mitochondrial clearance by enhancing Parkin recruitment to mitochondria

R. Ravindran, A. K. G. Velikkakath, N. D. Narendradev, A. Chandrasekharan, T. R. Santhoshkumar, S. M. Srinivasula

This study shows endosomes facilitate Parkin recruitment to mitochondria, a key step in mitophagy, by interacting with CARP2 before Parkin.

bioRxiv · Feb 19, 2020Cell Biology

Therapeutic efficacy of an immune stimulatory gene therapy strategy in a mouse model of high grade brainstem glioma

F. M. Mendez, P. Kadiyala, F. J. Nunez, S. Carney, F. Nunez, J. C. Gauss, R. Ravindran, S. Pawar, M. Edwards, P. Lowenstein, M. G. Castro

This paper tests an immune-stimulatory gene therapy in a mouse model of DIPG, showing increased survival and anti-tumor immunity through adenoviral delivery of TK and Flt3L.

bioRxiv · Nov 18, 2019 · PreprintCancer Biology

Paradigm of Vanadium pentoxide nanoparticle-induced autophagy and apoptosis in triple-negative breast cancer cells

P. R. P. Suma, R. A. Padmanabhan, S. R. Telukutla, R. Ravindran, A. K. G. Velikkakath, C. D. Dekiwadia, W. Paul, S. J. Shenoy, M. Laloraya, S. M. Srinivasula, S. V. Bhosale, R. S. Jayasree

This study investigates vanadium pentoxide nanoparticles' effects on triple-negative breast cancer cells, showing time-dependent antioxidant/pro-oxidant properties, lysosomal/mitochondrial accumulation, autophagy induction, and apoptosis, with no observed toxicity in mice.

bioRxiv · Oct 18, 2019 · PreprintScientific Communication & Education