Author

R. Rubinstein

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Biophysics· 1 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1 Approach:comparative / phylogenetic analysis· 1 Research Focus:development & morphogenesis· 1 Organism:Drosophila· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

G. Wiseglass· 2 shared B. Honig· 1 shared F. Bahna· 1 shared G. Ahlsen· 1 shared H. Dan· 1 shared K. M. Goodman· 1 shared K. Smorodinsky-Atias· 1 shared L. Shapiro· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersEvolutionary Biology

G. Wiseglass

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3 papers

Recent·Most cited

Following The Evolutionary Paths Of Highly Specific Homophilic Adhesion Proteins

G. Wiseglass, R. Rubinstein

This study investigates how Dscam1 proteins evolved strict homophilic specificity through evolutionary intermediates that allowed promiscuous interactions.

bioRxiv · Mar 18, 2024 · PreprintEvolutionary Biology

Clustered Protocadherin Cis-interactions are Required for Homophilic Combinatorial Cell-Cell Recognition Underlying Neuronal Self-Avoidance

G. Wiseglass, N. Boni, K. Smorodinsky-Atias, R. Rubinstein

The paper shows that cis-interactions of clustered protocadherins are essential for combinatorial cell-cell recognition, and mismatched isoforms disrupt trans complex stability, leading to neuronal self-avoidance.

bioRxiv · Nov 11, 2023 · PreprintBiochemistry

How clustered protocadherin binding specificity is tuned for neuronal self/non-self-recognition

K. M. Goodman, P. S. Katsamba, R. Rubinstein, G. Ahlsen, F. Bahna, S. Mannepalli, H. Dan, R. Sampogna, L. Shapiro, B. Honig

This study investigates cPcdh interactions, showing promiscuous cis dimers and precise trans homophilic interactions, supporting their role in neuronal self/non-self-recognition.

bioRxiv · Jul 22, 2021Biophysics