Arginine Di-methylation of RIPK3 Safeguards Necroptosis for Intestinal Homeostasis
J. Zhang, P. Zhao, H. Dan, Y. Wang, X. Chen, X. Jiang, Y. Shen, J. Wang, Z. Yang, J. Zhao, Y. Zhang, J. Zheng, W. Liu
This paper shows that arginine di-methylation of RIPK3 by PRMT5 prevents necroptosis in intestinal epithelial cells, maintaining homeostasis and preventing disease.
bioRxiv · Feb 21, 2024 · PreprintCell Biology