Urine-derived exosomes from individuals with IPF carry pro-fibrotic cargo.
S. Elliot, P. Catanuto, S. Pereira-Simon, X. Xia, S. Shahzeidi, E. Roberts, J. Ludlow, S. Hamdan, S. Daunert, J. Parra, R. Stone, I. Pastar, M. Tomic-Canic, M. K. Glassberg
The paper shows urine-derived exosomes from IPF patients carry pro-fibrotic miRNAs that induce fibrosis in skin and lung models.
bioRxiv · May 6, 2022Cell Biology