Author

R. Vazquez-Lombardi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Immunology· 5

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 5 Research Focus:cell type annotation· 4 Assay:scRNA-seq· 3 Research Focus:clustering· 2 Approach:deep learning· 2 Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Approach:genetic perturbation / CRISPR· 2

Frequent Co-Authors

S. T. Reddy· 5 shared F. Bieberich· 4 shared A. Yermanos· 3 shared C. R. Weber· 3 shared E. Kapetanovic· 3 shared R. B. Di Roberto· 3 shared B. Wagner· 2 shared D. M. Mason· 2 shared

Activity by Year

2020-2021 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

5 shared papersImmunology

S. T. Reddy

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

ImmunologybioRxivFeb 12, 2021

A single-cell atlas of lymphocyte adaptive immune repertoires and transcriptomes reveals age-related differences in convalescent COVID-19 patients

F. Bieberich, R. Vazquez-Lombardi, A. Yermanos…·S. T. Reddy

This study uses single-cell sequencing to analyze immune repertoires and transcriptomes in convalescent COVID-19 patients, revealing age-related differences in T and B cell responses.

DOI 10.3389/fimmu.2021.701085

humanscRNA-seq

𝕏 PostBluesky

ImmunologybioRxivPreprintFeb 12, 2021

Single-cell sequencing of plasma cells from COVID-19 patients reveals highly expanded clonal lineages produce specific and neutralizing antibodies to SARS-CoV-2

R. A. Ehling, C. R. Weber, D. M. Mason…·S. T. Reddy

Single-cell sequencing and screening identify expanded plasma cell clones in COVID-19 patients producing SARS-CoV-2-specific neutralizing antibodies.

DOI 10.1101/2021.02.12.430940

humanscRNA-seq

𝕏 PostBluesky

ImmunologybioRxivNov 9, 2020

Platypus: an open-access software for integrating lymphocyte single-cell immune repertoires with transcriptomes

A. Yermanos, A. Agrafiotis, J. Yates…·S. T. Reddy

Platypus integrates single-cell immune repertoires with transcriptomes to analyze lymphocyte features and transcriptional profiles in convalescent COVID-19 patients.

DOI 10.1093/nargab/lqab023

humanscRNA-seq

𝕏 PostBluesky

ImmunologybioRxivPreprintJun 23, 2020

CRISPR-targeted display of functional T cell receptors enables engineering of enhanced specificity and prediction of cross-reactivity

R. Vazquez-Lombardi, J. Jung, F. Bieberich…·S. T. Reddy

The paper introduces a CRISPR-based platform to engineer TCRs with enhanced specificity and predict cross-reactivity by profiling mutational landscapes and screening TCR libraries.

DOI 10.1101/2020.06.23.166363

humanproteomics

𝕏 PostBluesky

ImmunologybioRxivApr 30, 2020

A functional screening platform for engineering chimeric antigen receptors with reduced on-target, off-tumour activation

R. B. Di Roberto, R. C. Rueda, S. Frey…·S. T. Reddy

This study develops a functional screening platform to engineer CARs with reduced on-target, off-tumour activation by selecting for variants that respond only to high antigen expression.

DOI 10.1016/j.ymthe.2020.08.003

humangenetic perturbation / CRISPR

𝕏 PostBluesky