Cell BiologybioRxiv
LTBP1 promotes fibrillin incorporation into the extracellular matrix
M. Przyklenk, V. Georgieva, F. Metzen…·A. Schiavinato
This study shows LTBP1 coordinates fibrillin-1 and -2 incorporation into the extracellular matrix, with differential roles for its short and long isoforms, revealing a TGFβ-independent function in connective tissue homeostasis.
DOI 10.1016/j.matbio.2022.04.004