ImmunologybioRxiv
A Simplified Function-First Method for the Discovery and Optimization of Bispecific Immune Engaging Antibodies
S. McComb, A. Shepherd, B. Bennychen…·R. Weeratna
This paper introduces a high-throughput method for creating and evaluating bispecific T-cell engager antibodies (BITEs) using a simplified function-first approach to identify bioactive molecules without purification.
DOI 10.1371/journal.pone.0273884