ImmunologyNature CommunicationsPeer-reviewed
Myelin-reactive B cells exacerbate the severity of CD4+ T cell-driven CNS autoimmunity in an IL-23-dependent manner.
Mohamed Reda Fazazi, Prenitha Mercy Ignatius Arokia Doss, Resel Pereira…·Manu Rangachari
This study shows that MOG-specific B cells worsen CD4+ T cell-driven CNS autoimmunity by promoting Th17 and Tph cell accumulation via IL-23.
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