NeuroscienceFrontiers in NeurosciencePeer-reviewed
Dexmedetomidine - commonly used in functional imaging studies - increases susceptibility to seizures in rats but not in wild type mice
Aleksandra B Bortel, Roland Pilgram, Ze Shan Yao, Amir Shmuel
This study shows that dexmedetomidine increases seizure susceptibility in rats but not in mice, affecting hemodynamic and neurophysiological responses to stimulation.