PhysiologyInternational Journal of Molecular SciencesPeer-reviewed
Genetic Manipulation of Caveolin-1 in the Mouse Model of Marfan Syndrome Associated Aortic Root Aneurysm: Effects on Endothelial and Smooth Muscle Function
Tala Curry, Brikena Gusek, Ross M. Potter…·Mitra Esfandiarei
This study investigates the role of caveolin-1 in aortic root aneurysm development in MFS mice by examining its effects on endothelial and smooth muscle function, showing that Cav1 ablation increases NO production and improves aortic wall structure.
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