Author

Rudy Gelb-Bicknell

Harvard University

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Neuroscience· 1

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Assay:electronic health records· 1 Approach:experimental assay· 1 Organism:mouse· 1

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Andrew J. HolbrookiD· 1 shared Ava Devine· 1 shared Bradley T. HymaniD· 1 shared Ergina Agastra· 1 shared Haoyang Zhu· 1 shared Jasen Zhang· 1 shared Nina WolfiD· 1 shared Rachel E. BennettiD· 1 shared

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1 shared paperNeuroscience

Andrew J. HolbrookORCID

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1 paper

Recent·Most cited

NeurosciencebioRxivPreprintAug 10, 2025

Tau drives cell specific functional isolation of the hippocampal formation

Theodore J. Zwang, Jasen Zhang, Rudy Gelb-Bicknell…·Bradley T. Hyman

This study shows that tau accumulation leads to neuronal silencing and network dysfunction in the hippocampal formation without neuron loss, contributing to progressive network disruption.

1 citation

mouseelectronic health records

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