S. A. Boswell

This study integrates multi-omics data to identify DUB functions and therapeutic targets, revealing key enzymes like USP14, UCHL5, and USP7 with potential in cancer therapy.

Pick-Seq enables deep spatial transcriptomic profiling of fixed human tissue, revealing transcriptional differences in tumor invasion, proliferation, and immuno-editing.

This study compares the mechanisms of three FDA-approved CDK4/6 inhibitors and finds significant differences in their transcriptional, proteomic, and cellular effects, suggesting potential for differential clinical use.

The paper shows that tubulin mRNA stability changes with microtubule dynamics, responding to various physiological and toxic cues, and proposes a new genomic approach to study microtubule regulation.