Author

S. A. Clayton

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

A. R. Clark· 2 shared J. D. O'Neil· 2 shared K. K. Daley· 2 shared O. O. Bolimowska· 2 shared A. D. Mizner· 1 shared C. Lockwood· 1 shared C. S. Martin· 1 shared D. A. Tennant· 1 shared

Activity by Year

2023-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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2 shared papersImmunology

A. R. Clark

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

ImmunologybioRxivSep 20, 2023

The glucocorticoid dexamethasone inhibits HIF-1alpha stabilisation and metabolic reprogramming in lipopolysaccharide-stimulated primary macrophages.

S. A. Clayton, C. Lockwood, J. D. O'Neil…·A. R. Clark

This study shows dexamethasone inhibits HIF-1α stabilization and reduces GLUT1 expression in lipopolysaccharide-stimulated macrophages, impairing glucose uptake and metabolic reprogramming.

DOI 10.1093/discim/kyad027

mousehuman

𝕏 PostBluesky

Cancer BiologybioRxivJun 7, 2023

Sexual Dimorphism of Skeletal Muscle in a Mouse Model of Breast Cancer: A Functional and Molecular Analysis

L. E. Rentz, M. Whetsell, S. A. Clayton…·E. E. Pistilli

This study examines sexual dimorphism in skeletal muscle function and molecular composition in a mouse model of breast cancer, finding sex-specific transcriptome and contractile property differences.

DOI 10.3390/ijms241411669

mousebulk RNA-seq

𝕏 PostBluesky

ImmunologybioRxivPreprintMay 3, 2023

The glucocorticoid dexamethasone impairs the expression of anti-viral mediators in activated macrophages by inhibiting both expression and function of interferon beta.

J. D. O'Neil, O. O. Bolimowska, S. A. Clayton…·A. R. Clark

This study shows dexamethasone inhibits antiviral gene expression in macrophages by suppressing IFNβ expression and downstream interferon-regulated genes.

DOI 10.1101/2023.05.03.539212

mousehuman

𝕏 PostBluesky