A. R. Clark

This study identifies discrete inflammatory signatures driving thrombosis in the spleen and liver after Salmonella infection, revealing both organ-specific and shared mechanisms.

This study shows dexamethasone inhibits HIF-1α stabilization and reduces GLUT1 expression in lipopolysaccharide-stimulated macrophages, impairing glucose uptake and metabolic reprogramming.

This study shows dexamethasone inhibits antiviral gene expression in macrophages by suppressing IFNβ expression and downstream interferon-regulated genes.

This study identifies shear-sensing proteins in syncytiotrophoblast and models shear stress changes across gestation, suggesting early pregnancy mechanical stimuli influence placental development.

The paper uses single-cell RNA sequencing to identify early transcriptional changes in kidney cells after podocyte injury, revealing disrupted cell-cell interactions that contribute to chronic kidney disease progression.