Cell BiologybioRxiv
Misoprostol Treatment Prevents Hypoxia-Induced Cardiac Dysfunction Through a 14-3-3 and PKA regulatory motif on Bnip3
M. D. Martens, N. Seshadri, L. Nguyen…·J. W. Gordon
This study shows misoprostol prevents hypoxia-induced cardiac dysfunction by phosphorylating Bnip3, altering its localization and reducing necroinflammation and mitochondrial damage.
DOI 10.1038/s41419-021-04402-3