M. D. Martens

This study examines the effects of low- and high-dose doxorubicin on cardiac structure, function, and cell death pathways in mice, finding that high-dose DOX causes necrosis and autophagy inhibition, while low-dose activates caspase signaling.

This study shows misoprostol prevents hypoxia-induced cardiac dysfunction by phosphorylating Bnip3, altering its localization and reducing necroinflammation and mitochondrial damage.

This study shows misoprostol reduces neonatal cardiomyocyte proliferation via Bnip3 and calcium signaling, offering potential therapeutic benefits for neonatal heart conditions.

The paper shows that Nix-induced mitochondrial fission, mitophagy, and insulin resistance in myocytes are reversed by PKA phosphorylation.

This study shows misoprostol reduces Bnip3 expression and promotes alternative splicing to protect cells from hypoxia-induced damage by regulating calcium homeostasis.