BiophysicsbioRxivPreprint
Demultiplexing overlapping signaling scaffold functions to probe lipid messenger coupling to cytoskeletal dynamics.
N. J. Trenton, R. T. McLaughlin, S. Bellamkonda…·M. R. Diehl
This study uses live-cell imaging and statistical analyses to show IQGAP1 regulates actin dynamics around endosomes through PIP3-dependent tethering and transient inhibition of actin growth.