BiochemistryeLifePeer-reviewed
GFAT2 and AMDHD2 act in tandem to control the hexosamine biosynthetic pathway
V. Kroef, S. Ruegenberg, M. Horn…·M. S. Denzel
This study identifies AMDHD2 as a new regulator of the hexosamine biosynthetic pathway, showing it balances GFAT2 activity to control UDP-GlcNAc levels in mouse embryonic stem cells.
DOI 10.7554/elife.69223