Cell BiologybioRxiv
CEP290 myosin-tail homology domain is essential for protein confinement between inner and outer segments in photoreceptors
P. Datta, B. Hendrickson, S. Brendalen…·S. Seo
This study shows that the myosin-tail homology domain of CEP290 is essential for protein confinement between inner and outer segments in photoreceptors, with specific effects on RHO mislocalization and retinal degeneration.
DOI 10.1074/jbc.ra119.009712