Author

S. Britton

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Biophysics· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:host-pathogen & immune response· 2 Research Focus:protein folding & dynamics· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:DNA methylation· 1

Frequent Co-Authors

P. Calsou· 2 shared A. Adrait· 1 shared A. Devaux· 1 shared A. Nematbakhsh· 1 shared A. Pipier· 1 shared B. E. Barber· 1 shared C. Barthes· 1 shared C. Noirot· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersBiochemistry

P. Calsou

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Characterisation of Plasmodium vivax lactate dehydrogenase dynamics in P. vivax infections

P. Cao, S. Kho, M. J. Grigg, B. E. Barber, K. A. Piera, T. William, J. R. Poespoprodjo, I. K. Jang, J. A. Simpson, J. McCaw, N. M. Anstey, J. S. McCarthy, S. Britton

This study models PvLDH dynamics in P. vivax infections using Bayesian inference, finding significant differences between ex vivo and in vivo PvLDH levels and half-lives.

bioRxiv · Jun 12, 2023 · PreprintBiophysics

SDR enzymes oxidize specific lipidic alkynylcarbinols into cytotoxic protein-reactive species

P. Demange, E. Joly, J. Marcoux, P. R. A. Zanon, D. Listunov, P. Rulliere, C. Barthes, C. Noirot, J.-B. Izquierdo, K. Pradines, R. Hee, M. V. de Brito, M. Marcellin, R.-F. Serre, O. Bouchez, , S. Britton

The paper identifies SDR enzymes as bioactivators of lipidic alkynylcarbinols, converting them into cytotoxic electrophiles that modify proteins and induce cell death.

bioRxiv · Sep 15, 2021Biochemistry

Constrained G4 structures unveil topology specificity of known and new G4 binding proteins

A. Pipier, A. Devaux, T. Lavergne, A. Adrait, Y. Coute, S. Britton, P. Calsou, J.-F. Riou, E. Defrancq, D. Gomez

The paper identifies topology-specific G4-binding proteins using constrained G4 structures and reveals new interactions, including the NELF complex's role in G4-ligand effects.

bioRxiv · Apr 6, 2021Biochemistry

Role of combined cell membrane and wall mechanicalproperties regulated by polarity signals in cell budding

K. Tsai, S. Britton, A. Nematbakhsh, R. Zandi, W. Chen, M. Alber

This paper develops a 3D model to study how mechanical properties and polarity signals regulate yeast bud formation.

bioRxiv · Apr 30, 2020Biophysics