In silico and in vitro characterization of the mycobacterial protein Ku to unravel its role in non-homologous end-joining DNA repair
J. Baral, G. Bhattacharje, S. Dash, D. Samanta, E. Hinde, I. Rouiller, A. K. Das
The paper characterizes the DNA binding properties of mycobacterial Ku (mKu) and its role in NHEJ using in silico and in vitro methods, showing its ability to stabilize DNA and protect termini from degradation.
bioRxiv · Jun 7, 2023 · PreprintBiochemistry