Physiological activation of the nephron central command drives endogenous kidney tissue regeneration
G. Gyarmati, U. N. Shroff, A. Riquier-Brison, D. Desposito, W. Ju, A. Izuhara, S. Deepak, J. Burford, H. Kadoya, Y. Chen, M. Rinschen, N. Ahmadi, L. Lau, I. Gill, M. Kretzler, J. Peti-Peterdi
This study identifies a novel kidney regeneration mechanism triggered by physiological stress, involving macula densa cells controlling progenitor cells through secreted factors.
bioRxiv · Dec 7, 2021Physiology