A. James

Female-dominated disciplines have lower evaluated research quality and funding success rates, for men and women

The paper finds that female-dominated disciplines have lower research quality evaluations and funding success rates, affecting both men and women.

Genomic and ecologic characteristics of the airway microbial-mucosal complex

The paper characterizes the genomic and ecological features of the airway microbial-mucosal complex, identifying novel bacteria and functional pathways linked to lung diseases.

CNTNAP4 signaling regulates osteosarcoma disease progression

This study shows that CNTNAP4 signaling promotes osteosarcoma progression, and its deletion reduces tumor growth, angiogenesis, and metastasis.

Neuron-like function of the nephron central command

The paper identifies the macula densa cells in the kidney as neuron-like structures with functions similar to interoceptive neurons, regulating organ functions through local neural networks.

Macrophage proliferation machinery leads to PDAC progression, but susceptibility to innate immunotherapy.

This study shows that TAM proliferation in PDAC is driven by CSF1 from fibroblasts, leading to immunosuppression and tumor progression, but also increasing sensitivity to CD40 agonist therapy.

Obtaining Spatially Resolved Tumor Purity Maps Using Deep Multiple Instance Learning In A Pan-cancer Study

This paper develops a deep multiple instance learning model to predict tumor purity from histopathology slides, showing spatial variation and improving sample selection for genomic analysis.

Genetic determinism of phage-bacteria coevolution in natural populations

The paper investigates phage-bacteria coevolution in natural populations, finding that phage and host genomes exhibit gene content variation and that negative-frequency dependent selection drives coevolutionary dynamics.

The multidimensional nutritional niche of fungus-cultivar provisioning in free-ranging colonies of a neotropical leafcutter ant

This study examines how the nutritional requirements of a fungal cultivar influence the foraging behavior of Atta colombica leafcutter ants in a Panamanian rainforest.

Cooperative and non-cooperative behaviour in the exploitation of a common renewable resource with environmental stochasticity

This paper models cooperative and non-cooperative fishing behavior under environmental noise using stochastic optimization and agent-based simulations to assess the impact of noise on fishery sustainability and cooperation.

Regulation of heterotopic ossification through local inflammatory monocytes in a mouse model of aberrant wound healing

This study identifies TGFβ1-producing monocytes/macrophages as drivers of heterotopic ossification in a mouse model and shows CD47 activation can reduce HO by modulating these cells.

Kia kaua te reo e rite ki te moa, ka ngaro: Do not let the language suffer the same fate as the moa

The paper develops a model to predict language extinction or recovery by analyzing proficiency transitions, showing Welsh may thrive while te reo Māori faces extinction without intervention.

Distinctive airway microbial ecology of smokers and asthmatics

The paper examines airway microbial communities in smokers and asthmatics, finding smoking reduces diversity and alters bacterial networks, while asthma shows more targeted microbial changes.