Transcriptomic Profiling of Plasma Extracellular Vesicles Enables Reliable Annotation of the Cancer-specific Transcriptome and Molecular Subtype
V. Bahrambeigi, J. J. Lee, V. Branchi, J. T. Henry, K. I. Rajapakshe, B. M. Stephens, S. Dhebat, M. W. Hurd, R. Sun, P. Yang, W. Wang, S. E. Kopetz, A. Maitra, P. A. Guerrero, Z. Xu, , E. Ruppin
This study uses deep learning on plasma extracellular vesicle RNA to predict cancer subtypes, monitor treatment effects, and identify gene fusions and neoepitopes without tissue sampling.
bioRxiv · Oct 27, 2022Cancer Biology