A mitochondrial sirtuin shapes the intestinal microbiota by controlling lysozyme expression
M. Knop, C. Treitz, S. Bettendorf, J. Bossen, J. von Frieling, S. Doms, I. Bruchhaus, R. Kuehnlein, J. F. Baines, A. Tholey, T. Roeder
This study shows that dSirt4 in Drosophila controls lysozyme expression in the intestine, altering microbiota composition and reducing lifespan.
bioRxiv · Jun 2, 2023 · PreprintCell Biology