BiochemistrybioRxiv
Mycolactone enhances the Ca2+ leakage from endoplasmic reticulum by trapping Sec61 translocons in a Ca2+ permeable state
P. Bhadra, S. Dos Santos, I. Gamayun…·A. Cavalie
This study shows mycolactone enhances Ca2+ leakage from the ER by trapping Sec61 translocons in a Ca2+ permeable state, leading to ER Ca2+ depletion.
DOI 10.1042/bcj20210345