Author

S. Franck

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Research Focus:differential expression· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

A. Keller· 2 shared C. Markouli· 2 shared C. Spits· 2 shared D. Dziedzicka· 2 shared E. Couvreu De Deckersberg· 2 shared K. Sermon· 2 shared M. Geens· 2 shared A. Gheldof· 1 shared

Activity by Year

2020-2020 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersCell Biology

A. Keller

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Endogenous suppression of WNT signalling in human embryonic stem cells leads to low differentiation propensity towards definitive endoderm

D. Dziedzicka, M. Tewary, A. Keller, L. Tilleman, L. Prochazka, J. Östblom, E. Couvreu De Deckersberg, C. Markouli, S. Franck, F. Van Nieuwerburgh, C. Spits, P. W. Zandstra, K. Sermon, M. Geens

The paper shows that endogenous suppression of WNT signaling in hPSCs reduces differentiation efficiency towards definitive endoderm, and that increasing WNT or inhibiting PI3K/AKT can overcome this block.

bioRxiv · Jul 3, 2020Cell Biology

Constitutional activation of BMP4 and WNT signalling in hESC results in impaired mesendoderm differentiation

C. Markouli, E. Couvreu De Deckersberg, D. Dziedzicka, M. Regin, S. Franck, A. Keller, A. Gheldof, M. Geens, K. Sermon, C. Spits

The paper identifies a human embryonic stem cell subline with hyperactivated WNT and BMP4 signaling that impairs mesendoderm differentiation, leading to trophoblast-like cell formation.

bioRxiv · Jun 4, 2020 · PreprintCell Biology

Boosting Toll-like receptor 4 signaling enhances the therapeutic outcome of antibiotic therapy in pneumococcal pneumonia

F. Casilag, S. Franck, L. Matarazzo, M. Figeac, R. Michelet, C. Kloft, C. Carnoy, J.-C. Sirard

This study shows that combining TLR4 activation with antibiotics improves bacterial clearance and survival in pneumococcal pneumonia.

bioRxiv · Feb 18, 2020 · PreprintMicrobiology