Author

M. Regin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:clustering· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

C. Spits· 3 shared E. Couvreu de Deckersberg· 3 shared D. Al Delbany· 2 shared K. Sermon· 2 shared N. Krivec· 2 shared Y. Lei· 2 shared A. Gheldof· 1 shared A. Keller· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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3 shared papersCell Biology

C. Spits

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Gain of 1q confers an MDM4-driven growth advantage to undifferentiated and differentiating hESC while altering their differentiation capacity

N. Krivec, E. Couvreu de Deckersberg, Y. Lei, D. Al Delbany, M. Regin, S. Verhulst, L. A. van Grunsven, K. Sermon, C. Spits

This study shows that 1q gain in hESCs increases MDM4 expression, giving a growth advantage during differentiation by reducing DNA damage sensitivity and altering differentiation capacity.

bioRxiv · Sep 19, 2023Cell Biology

SALL3 mediates the loss of neuroectodermal differentiation potential in human embryonic stem cells with chromosome 18q loss

C. Spits, Y. Lei, D. Al Delbany, N. Krivec, M. Regin, E. Couvreu de Deckersberg, C. Janssens, M. Ghosh, K. D. Sermon

This study shows that loss of chromosome 18q in human embryonic stem cells impairs neuroectoderm commitment and cardiac progenitor differentiation through SALL3 downregulation.

bioRxiv · Jun 26, 2023 · PreprintCell Biology

Constitutional activation of BMP4 and WNT signalling in hESC results in impaired mesendoderm differentiation

C. Markouli, E. Couvreu De Deckersberg, D. Dziedzicka, M. Regin, S. Franck, A. Keller, A. Gheldof, M. Geens, K. Sermon, C. Spits

The paper identifies a human embryonic stem cell subline with hyperactivated WNT and BMP4 signaling that impairs mesendoderm differentiation, leading to trophoblast-like cell formation.

bioRxiv · Jun 4, 2020 · PreprintCell Biology