Cell BiologybioRxivPreprint
The neuropeptide alpha calcitonin gene-related peptide impairs load-stimulated proteoglycan production of human chondrocytes via WNT activity
Helen F. Dietmar, Nicole Hecht, C. Binder…·S. Diederichs
This study shows that CGRP impairs load-stimulated proteoglycan production in human chondrocytes by modulating WNT activity, suggesting a new therapeutic target for osteoarthritis.
DOI 10.1101/2024.10.11.617807