Author

S. Guseva

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1 Organism:virus· 1

Frequent Co-Authors

A. K. Rangadurai· 2 shared A. Manghrani· 2 shared H. Al-Hashimi· 2 shared O. Szekely· 2 shared A. R. Camacho-Zarco· 1 shared B. Liu· 1 shared D. Maurin· 1 shared E. Mikkola· 1 shared

Activity by Year

2023-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersBiochemistry

A. K. Rangadurai

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3 papers

Recent·Most cited

Quantitative and systematic NMR measurements of sequence-dependent A-T Hoogsteen dynamics uncovers unique conformational specificity in the DNA double helix

A. Manghrani, A. K. Rangadurai, O. Szekely, B. Liu, S. Guseva, H. Al-Hashimi

This study measures sequence-dependent A-T Hoogsteen dynamics in DNA using NMR, revealing distinct conformational specificity and sequence dependence.

bioRxiv · May 15, 2024 · PreprintBiochemistry

A specific phosphorylation-dependent conformational switch of SARS-CoV-2 nucleoprotein inhibits RNA binding

M. Botova, A. R. Camacho-Zarco, J. Tognetti, L. M. Bessa, S. Guseva, E. Mikkola, N. Salvi, D. Maurin, T. Herrmann, M. Blackledge

This study identifies a phosphorylation-dependent conformational switch in SARS-CoV-2 nucleoprotein that inhibits RNA binding by altering domain interactions.

bioRxiv · Feb 22, 2024 · PreprintBiochemistry

NMR measurements of transient low-populated tautomeric and anionic Watson-Crick-like G·T/U in RNA:DNA hybrids: Implications for the fidelity of transcription and CRISPR/Cas9 gene editing

O. Szekely, A. K. Rangadurai, S. Gu, A. Manghrani, S. Guseva, H. Al-Hashimi

This study uses NMR to show that G*T/U mismatches in RNA:DNA hybrids can form Watson-Crick-like conformations, potentially contributing to transcription errors and CRISPR/Cas9 off-target effects.

bioRxiv · Aug 24, 2023Biophysics