Author

S. Hoehl

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 3 Organism:human· 3 Assay:proteomics· 3 Organism:virus· 2 Assay:bulk RNA-seq· 1 Approach:statistical model· 1 Research Focus:variant calling· 1

Frequent Co-Authors

S. Ciesek· 5 shared A. Muik· 3 shared B. G. Lui· 3 shared K. Grikscheit· 3 shared M. Bacher· 3 shared O. Ozhelvaci· 3 shared O. Tuereci· 3 shared U. Sahin· 3 shared

Activity by Year

2020-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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Curved chords = mutual co-authorship

5 shared papersImmunology

S. Ciesek

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Progressive loss of conserved spike protein neutralizing antibody sites in Omicron sublineages is balanced by preserved T-cell recognition epitopes

A. Muik, B. G. Lui, H. Diao, Y. Fu, M. Bacher, A. Toker, J. Grosser, O. Ozhelvaci, K. Grikscheit, S. Hoehl, N. Kohmer, Y. Lustig, G. Regev-Yochay, S. Ciesek, K. Beguir, , U. Sahin

The paper examines how Omicron sublineages evade neutralizing antibodies but retain T-cell epitopes, suggesting T-cell immunity remains effective against these variants.

bioRxiv · Dec 15, 2022 · PreprintImmunology

Omicron BA.2 breakthrough infection enhances cross-neutralization of BA.2.12.1 and BA.4/BA.5

A. Muik, B. G. Lui, M. Bacher, A.-K. Wallisch, A. Toker, A. Finlayson, K. Krueger, O. Ozhelvaci, K. Grikscheit, S. Hoehl, S. Ciesek, O. Tuereci, U. Sahin

The paper shows that BA.2 breakthrough infection in vaccinated individuals enhances neutralization of BA.2.12.1 and BA.4/BA.5 compared to BA.1 breakthrough infection.

bioRxiv · Aug 2, 2022Immunology

Omicron breakthrough infection drives cross-variant neutralization and memory B cell formation

J. Quandt, A. Muik, N. Salisch, B. G. Lui, S. Lutz, K. Krueger, A.-K. Wallisch, P. Adams-Quack, M. Bacher, A. Finlayson, O. Ozhelvaci, I. Vogler, K. Grikscheit, S. Hoehl, U. Goetsch, , U. Sahin

bioRxiv · Apr 1, 2022 · PreprintImmunology

Evaluation of stability and inactivation methods of SARS-CoV-2 in context of laboratory settings

S. Westhaus, M. Widera, H. Rabenau, S. Hoehl, D. Bojkova, J. Cinatl, S. Ciesek

This study evaluates inactivation methods for SARS-CoV-2 in laboratory settings, finding that some lysis buffers and chemical treatments effectively inactivate the virus, while others do not.

bioRxiv · Sep 11, 2020Microbiology

Optimized qRT-PCR approach for the detection of intra- and extracellular SARS-CoV-2 RNAs

T. Toptan, S. Hoehl, S. Westhaus, D. Bojkova, A. Berger, B. Rotter, K. Hoffmeier, S. Ciesek, M. Widera

This study presents an optimized qRT-PCR method for detecting SARS-CoV-2 RNA using a low-cost SYBR green approach, showing improved detection limits and simplicity compared to multi-step assays.

bioRxiv · Apr 20, 2020Microbiology