ImmunologybioRxiv
RIG-I immunotherapy overcomes radioresistance in p53-positive malignant melanoma
S. Lambing, S. Holdenrieder, P. Müller…·M. Renn
This study shows that RIG-I ligands enhance radiation-induced tumor cell death and immunogenicity in melanoma, with p53 playing a key role in the synergy between RIG-I and radiation.