Author

S. J. Melchor

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:host-pathogen & immune response· 2 Assay:imaging· 1 Research Focus:metabolism & bioenergetics· 1 Assay:metabolomics· 1

Frequent Co-Authors

S. E. Ewald· 2 shared A. E. Ross· 1 shared A. G. Ball· 1 shared A. W. L. Kinman· 1 shared B. D. Groff· 1 shared C. M. Saunders· 1 shared D. Abebayehu· 1 shared E. A. LaTorre Castillo· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersImmunology

S. E. Ewald

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

ImmunologybioRxivPreprintDec 20, 2022

Tricarboxylic acid (TCA) cycle, sphingolipid, and phosphatidylcholine metabolism are dysregulated in T. gondii infection-induced cachexia

T.-Y. Feng, S. J. Melchor, H. Ghumman…·S. E. Ewald

The paper identifies metabolic dysregulation in T. gondii infection-induced cachexia, showing increased sphingolipids and phosphatidylcholines and decreased TCA cycle intermediates in mouse sera.

DOI 10.1101/2022.12.20.521281

mousemetabolomics

𝕏 PostBluesky

ImmunologybioRxivDec 28, 2020

Acute lymph node slices are a functional model system to study immunity ex vivo

M. C. Belanger, A. G. Ball, M. A. Catterton…·R. R. Pompano

This study validates live murine lymph node slices as a functional ex vivo model to study immune responses while preserving spatial organization and dynamic accessibility.

DOI 10.1021/acsptsci.0c00143

mouseimaging

𝕏 PostBluesky

ImmunologybioRxivPreprintSep 26, 2019

Cachexia and fibrosis are costs of chronic IL-1R-mediated disease tolerance in T. gondii infection

S. E. Ewald, S. J. Melchor, J. A. Hatter…·S. Countermarsh-Ott

This study shows that IL-1R signaling protects mice from acute T. gondii infection but leads to chronic cachexia and fibrosis when sustained.

DOI 10.1101/783316

mouseexperimental assay

𝕏 PostBluesky