S. J. Payne

This paper develops a computational framework to generate cerebral perfusion models using MRI data for simulating cerebral blood flow in healthy and ischaemic stroke scenarios, showing strong correlations with anatomical and haemodynamic measurements.

This study investigates how microvascular occlusions in cerebral arterioles cause distant hypoxia using rodent experiments and human vascular simulations.

This study evaluates a 3D porous cerebral perfusion model for stroke treatment, finding that coarse grids with first-order elements reliably estimate perfusion but higher-order elements are needed for accurate flow rate calculations.