Cancer BiologybioRxiv
KMT2D Links TGF-β Signalling to Non-Canonical Activin Pathway and Regulates Pancreatic Cancer Cell Plasticity
S. Lu, H. S. Kim, Y. Cao…·J. Shi
This study identifies KMT2D as a tumor suppressor in pancreatic cancer, linking TGF-β signaling to the non-canonical activin A pathway through miR-147b and showing its role in cancer cell plasticity and metastasis.
DOI 10.1002/ijc.34528